2002 research grants

Dedicated in loving memory of
Maureen Welch Grogran

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Maureen's Story

 

Development of a Novel Adjunct to X-Ray Mammography


Principal Investigator: David Feiglin, MD, FACP, FRCPC
Co-Investigator: Andrzej Krol, PhD

 

Conventional mammography although thte best screen test to detect early breast cancer cannot tell the difference between benign and malignant changes in the breast causing large number of women to have a biopsy of the breast to tell the difference. This is emotionally draining and costly for these women. Drs. Feiglin and Krol have received a $50,00 grant to see if photon emission tomography (PET) scans can tell benign from malignant disease well enough to reduce the number of breast biopsies without missing cancers.

 

 

Dedicated in loving memory of
Kathleen Williams Virginia

kwv

Kathleen's Story

 

Tumor-Osteoclast Signaling in Osteolytic Bone Metastases


Principal Investigator: Matthew J. Allen, Vet, MD, PhD
Co-Investigator: Timothy A. Damron, MD

 

Spread of breast cancer to bones, bony metastases, are a cause of significant pain and disability in women with advanced breast cancer. Although radiotherapy (x-ray treatment) is often very effective at killing the cancer cells it does not heal the bone. Drs. Matt Allen and Tim Damon have been given a $50,000 grant to study two molecules that can signal bone cells to re-grow and the effects of two drugs that may help activate those cells.

 

Dedicated in loving memory of
Michaela Smits Cardinall

Michaela Smits Cardinall

Michaela's Story

 

Association of Mouse Mammary Tumor Virus (MMTV) with Human Breast Cancer


Principal Investigator: Bernard J. Poiesz, MD
Co-Investigators: David Dugan, MD, Sheila Lemke, MD, Steven Landas, MD, Raisa Perzova, PhD

 

Viruses are known to induce certain cancers. For years there has been a concern that mouse mammary tumor virus (MMTV) has such a link to human breast cancer. Dr. Poiesz and his colleagues have been developing an excellent assay for this virus that should be able to answer this question. Dr. Poiesz has received a $50,000 grant to perfect this assay and study the large number of human benign and malignant breast tumors already in their laboratory to see if this virus is present in cancer and not in benign disease. This grant has already assisted Dr. Poiesz in obtaining a much larger grant to look at this on a much larger group of patients.